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研究業績

  • 100. Inositol trisphosphate/Ca2+ as messengers of bradykinin B2 and muscarinic acetylcholine m1-m4 receptors in neuroblastoma-derived hybrid cells.
    Noda M, Ishizaka N, Yokoyama S, Hoshi N, Kimura Y, Hashii M, Taketo M, Egorova A, Knijnik R, Fukuda K, Morikawa H, Brown DA, Higashida H.
    J Lipid Mediat Cell Signal. 14(1-3): 175-185, 1996.
  • 99. Streptozotocin, an inducer of NAD+ decrease, attenuates M-potassium current inhibition by ATP, bradykinin, angiotensin II, endothelin 1 and acetylcholine in NG108-15 cells.
    Higashida H, Egorova A, Hoshi N, Noda M.
    FEBS Lett. 379(3): 236-238, 1996.
  • 98. Bradykinin B2 receptors and signal transduction analyzed in NG108-15 neuroblastoma x glioma hybrid cells, B2 receptor-transformed CHO cells and ras-transformed NIH/3T3 fibroblasts.
    Higashida, H, Hashii M, Yokoyama S, Taketo M, Hoshi N, Noda M, Zhong ZG, Shahidullah M, Minabe Y, Nakashima S, Nozawa Y.
    Prog Brain Res. 113: 215-230, 1996.
  • 97. cDNA cloning and functional characterization of rat intestinal monocarboxylate transporter.
    Takanaga H, Tamai I, Inaba S, Sai Y, Higashida H, Yamamoto H, Tsuji A.
    Biochem Biophys Res Commun. 217(1): 370-377, 1995.
  • 96. Microheterogeneity in heteromultimeric assemblies formed by Shaker (Kv1) and Shaw (Kv3) subfamilies of voltage-gated K+ channels.
    Shahidullah M, Hoshi N, Yokoyama S, Higashida H.
    Proc Biol Sci. 261(1362): 309-317, 1995.
  • 95. Participation of a proton-cotransporter, MCT1, in the intestinal transport of monocarboxylic acids.
    Tamai I, Takanaga H, Maeda H, Sai Y, Ogihara T, Higashida H., Tsuji A.
    Biochem Biophys Res Commun. 214(2): 482-489, 1995.
  • 94. Slow inactivation conserved in heteromultimeric voltage-dependent K+ channels between Shaker (Kv1) and Shaw (Kv3) subfamilies.
    Shahidullah M, Hoshi N, Yokoyama S, Kawamura T, Higashida H.
    FEBS Lett. 371(3): 307-310, 1995.
  • 93. Whole-cell analysis of NGK2 (mKv3.1a) K+ channels stably expressed in mouse fibroblast cells.
    Kawamura T, Enomoto K, Yokoyama S, Hoshi N, Yamashita J, Higashida H.
    Neurosci Lett. 197(2): 164-166, 1995.
  • 92. Coupling of the cloned mu-opioid receptor with the omega-conotoxin-sensitive Ca2+ current in NG108-15 cells.
    Morikawa H, Fukuda K, Kato S, Mori K, Higashida H.
    J Neurochem. 65(3): 1403-1406, 1995.
  • 91. Mouse B2 bradykinin receptor gene maps to distal chromosome 12.
    Taketo M, Yokoyama S, Rochelle J, Kimura Y, Higashida H, Taketo M, Seldin MF.
    Genomics. 27(1): 222-223, 1995.
  • 90. Functional expression of transporter for beta-lactam antibiotics and dipeptides in Xenopus laevis oocytes injected with messenger RNA from human, rat and rabbit small intestines.
    Tamai I, Tomizawa N, Takeuchi T, Nakayama K, Higashida H, Tsuji A.
    J Pharmacol Exp Ther. 273(1): 26-31, 1995.
  • 89. Discrete acetylcholine release from neuroblastoma or hybrid cells overexpressing choline acetyltransferase into the neuromuscular synaptic cleft.
    Zhong ZG, Kimura Y, Noda M, Misawa H, Higashida H.
    Neurosci Res. 22(1): 81-88, 1995.
  • 88. Nicotinamide-adenine dinucleotide regulates muscarinic receptor-coupled K+ (M) channels in rodent NG108-15 cells.
    Higashida H, Robbins J, Egorova A, Noda M, Taketo M, Ishizaka N, Takasawa S, Okamoto H, Brown DA.
    J Physiol. 482 ( Pt 2): 317-323, 1995.
  • 87. Inositol 1,4,5-trisphosphate formation and ryanodine-sensitive oscillations of cytosolic free Ca2+ concentrations in neuroblastoma x fibroblast hybrid NL308 cells expressing m2 and m4 muscarinic acetylcholine receptor subtypes.
    Ishizaka N, Noda M, Kimura Y, Hashii M, Fukuda K, Katayama M, Brown DA, Higashida H.
    Pflugers Arch. 429(3): 426-433, 1995.
  • 86. Overexpression of choline acetyltransferase reconstitutes discrete acetylcholine release in some but not all synapse formation-defective neuroblastoma cells.
    Zhong ZG, Misawa H, Furuya S, Kimura Y, Noda M, Yokoyama S, Higashida H.
    J Physiol Paris. 89(3): 137-145, 1995.
  • 85. Functional expression of intestinal dipeptide/beta-lactam antibiotic transporter in Xenopus laevis oocytes.
    Tamai I, Tomizawa N, Kadowaki A, Terasaki T, Nakayama K, Higashida H, Tsuji A.
    Biochem Pharmacol. 48(5): 881-888, 1994.
  • 84. Distinct induction of c-fos mRNA in NG108-15 cells transfected with muscarinic m1 and m3 receptors.
    Tohda M, Tohda C, Sakuma S, Higashida H, Nomura Y.
    Eur J Pharmacol. 268(2): 169-176, 1994.
  • 83. Activation of inward current associated with M-potassium current inhibition in m1-muscarinic receptor-transformed NG108-15 cells by KST-5452, a novel cognition enhancer.
    Kishida H, Yamamoto K, Fuse Y, Noda M, Higashida H.
    Neurosci Lett. 172(1-2): 119-121, 1994.
  • 82. Ca2+ influx gated by inositol-3,4,5,6-tetrakisphosphate in NIH/3T3 fibroblasts.
    Hashii M, Hirata M, Ozaki S, Nozawa Y, Higashida H.
    Biochem Biophys Res Commun. 200(3): 1300-1306, 1994.
  • 81. Sodium channel mRNAs in cultured spinal cord astrocytes: in situ hybridization in identified cell types.
    Black JA, Yokoyama S, Waxman SG, Oh Y, Zur KB, Sontheimer H, Higashida H, Ransom BR.
    Brain Res Mol Brain Res. 23(3): 235-245, 1994.
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